Wednesday, December 24, 2008

anemia



Definition
Anemia can be classified according to several criteria, but the most
is a practical way of grouping based on the occurrence of post-Anemia
bleeding, anemia hemolitik, defisiensi anemia, anemia and anemia aplastik
because of violence.
CAUSE
Production of blood that is not enough (because defisiensi or bone marrow failure),
excessive blood loss, excessive destruction of blood or a combination
from these factors.
Loss of blood and chronicles the secret, for example, in ankilostomiasis,
cause anemia defisiensi Fe, while the other occurred between hemolisis
defisiensi on G6PD and talasemia.
Clinical Overview
- Anemia due to the sudden loss of blood and many will
homeostatis compensation body. Acute blood loss as much as 12 - 15%
will give the symptoms of pale, takikardia with normal blood pressure or
low. Lost 15 - 20% cause blood pressure to drop
shock, and 20% loss can result in death.
- Anemia defisiensi marked with a limp, often pulse, tired and grouchy
headaches. Papil appear atrofi tongue. Heart swell and sometimes sounds
murmur sistolik. At the edge of the blood picture appear anemic and hipokrom
mikrositer, while low serum iron content.
- Defisiensi acid and vitamin B12 anemia folat cause megaloblastik
which may be accompanied by neurological symptoms.
- Anemia hemolitik be followed by an increase in blood bilirubin (ikterus).
Spleen is generally limited.
- Anemia aplastik visible from the low rate of Hb and other systemic symptoms,
without enlarging the organ.
Diagnosis
Inspection rate and blood Hb edge.
general Hb <12 g / dl.
Treatment guidelines in the Basic health 2007
15
Dealing
- Successful treatment depends greatly on the ability to enforce
on the level of early diagnosis.
- Anemia pascaperdarahan overcome by transfusion of 10 - 20
ml / kgBB, or plasma expander. If there is no both, intravenous fluids
the other can also be used.
- Impact of slow can be overcome with packed red cell transfusion.
- Anemia defisiensi iron overcome with adequate food, sulfas ferosus
10 mg / day kgBB 3 x Iron or shut 1mg/kgBB/hari
- Anemia megaloblastik specific treatment, therefore, must be distinguished
cause, defisiensi vitamin B12 or defisiensi acid folat.
Doses of vitamin B12 100 mcg / day im, for 5 - 10 days as initial therapy
followed by therapy rumat 100-200 mcg / be achieved remisi until months.
Dose of acid folat 0.5 - 1mg/hari in oral for 10 days, resumed
with 0.1 to 0.5 mg / day.
The use of oral vitamin B12 is not no use in anemia pernisiosa.
In addition, the thin oral more expensive.
- Hemolisis autoimun overcome by prednison 2 - 5 mg / kgBB / day and peroral
testosteron 1 - 2 mg / kgBB / day iv, for the long term.
- Blood transfusion given only when it is needed.
- Refer to the hospital
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